Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Palmar-plantar erythrodysaesthesia syndrome
ADR ID BADD_A03260
ADR Hierarchy
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.07      Sensory abnormalities NEC
17.02.07.009      Palmar-plantar erythrodysaesthesia syndrome
23      Skin and subcutaneous tissue disorders
23.07      Skin and subcutaneous tissue disorders NEC
23.07.04      Skin and subcutaneous conditions NEC
23.07.04.001      Palmar-plantar erythrodysaesthesia syndrome
Description Not Available
MedDRA Code 10033553
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Hand and foot syndrome | Hand-and-foot syndrome | Palmar-plantar erythrodysaesth. | Palmar-plantar erythrodysaesthesia syndrome | Hand and foot syndrome secondary to chemotherapy | Palmar-plantar erythrodysesthesia syndrome | Palmar-plantar erythema | Hand and foot skin reaction | Acral erythema | Genital erythrodysesthesia | Genital erythrodysaesthesia | Toxic erythema of chemotherapy
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Broad substrate specificity ATP-binding cassette transporter ABCG2Q9UNQ0T56556
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00931Fluorouracil0.012231%
BADD_D00967Fosinopril--
BADD_D01009Gemcitabine0.004795%
BADD_D01110Hydroxyurea--
BADD_D01119Ibrutinib--
BADD_D01127Idarubicin--
BADD_D01130Idelalisib--
BADD_D01133Ifosfamide--
BADD_D01136Imatinib--
BADD_D01137Imatinib mesylate--
BADD_D01195Irinotecan--
BADD_D01196Irinotecan hydrochloride--
BADD_D01222Ixabepilone--
BADD_D01245Lansoprazole--
BADD_D01248Lapatinib0.005595%
BADD_D01253Lenalidomide--
BADD_D01254Lenvatinib0.044491%
BADD_D01257Letrozole0.003691%
BADD_D01258Leucovorin0.008747%
BADD_D01285Levothyroxine--
BADD_D01393Meropenem0.000213%
BADD_D01401Metformin--
BADD_D01435Methylprednisolone hemisuccinate--
BADD_D01511Nabumetone0.000737%
BADD_D01567Nilotinib--
BADD_D01629Osimertinib--
BADD_D01633Oxaliplatin--
BADD_D01653Paclitaxel0.011988%
BADD_D01654Palbociclib--
BADD_D01655Palifermin--
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